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SLC1A5 SLC1A5 SLC7A5 SLC7A5 SLC7A1 SLC7A1 SLC38A2 SLC38A2 SLC3A2 SLC3A2 GLS-2 GLS-2 SLC6A14 SLC6A14 GLS2 GLS2 SLC2A1 SLC2A1 SLC38A1 SLC38A1 SLC7A8 SLC7A8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
SLC1A5Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. (539 aa)    
Predicted Functional Partners:
SLC7A5
Solute carrier family 7 member 5.
   
  
 0.954
SLC7A1
Solute carrier family 7 member 1.
   
  
 0.846
SLC38A2
Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta (By similarity).
   
 
 0.805
SLC3A2
Solute carrier family 3 member 2.
   
 
 0.803
GLS-2
ANK_REP_REGION domain-containing protein.
   
  
 0.781
SLC6A14
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
  
  
 0.778
GLS2
Glutaminase 2.
   
  
 0.777
SLC2A1
Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain.
   
  
 0.767
SLC38A1
Solute carrier family 38 member 1.
    
 
 0.758
SLC7A8
Solute carrier family 7 member 8.
      
 0.758
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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