STRINGSTRING
GALK1 GALK1 GALT GALT GALM GALM GALE GALE UGP2 UGP2 PGM1 PGM1 DHDH DHDH GMPPA GMPPA UAP1 UAP1 PGM2L1 PGM2L1 TGDS TGDS
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GALK1Galactokinase; Major enzyme for galactose metabolism; Belongs to the GHMP kinase family. GalK subfamily. (392 aa)    
Predicted Functional Partners:
GALT
Galactose-1-phosphate uridylyltransferase.
 0.999
GALM
Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
 
 0.998
GALE
UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...]
  
 0.990
UGP2
UTP--glucose-1-phosphate uridylyltransferase; Plays a central role as a glucosyl donor in cellular metabolic pathways; Belongs to the UDPGP type 1 family.
  
 
 0.872
PGM1
Phosphoglucomutase-1; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
    
 0.803
DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.
  
 
 0.776
GMPPA
GDP-mannose pyrophosphorylase A.
  
  
 0.644
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1.
  
 
 0.607
PGM2L1
Phosphoglucomutase 2 like 1.
    
 0.601
TGDS
dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
   
  
 0.584
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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