node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BOP1 | EBNA1BP2 | ENSBTAP00000012938 | ENSBTAP00000028708 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | EBNA1 binding protein 2. | 0.996 |
BOP1 | MAK16 | ENSBTAP00000012938 | ENSBTAP00000044825 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Protein MAK16 homolog. | 0.979 |
BOP1 | MRTO4 | ENSBTAP00000012938 | ENSBTAP00000015861 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.997 |
BOP1 | NIFK | ENSBTAP00000012938 | ENSBTAP00000031516 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.990 |
BOP1 | NIP7 | ENSBTAP00000012938 | ENSBTAP00000002182 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. | 0.976 |
BOP1 | NOC2L | ENSBTAP00000012938 | ENSBTAP00000021980 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.999 |
BOP1 | PES1 | ENSBTAP00000012938 | ENSBTAP00000010163 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
BOP1 | RSL1D1 | ENSBTAP00000012938 | ENSBTAP00000019422 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage; Belongs to the universal ribosomal protein uL1 family. Highly divergent. | 0.994 |
BOP1 | WDR12 | ENSBTAP00000012938 | ENSBTAP00000020499 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.999 |
BOP1 | WDR74 | ENSBTAP00000012938 | ENSBTAP00000012489 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL. | 0.998 |
EBNA1BP2 | BOP1 | ENSBTAP00000028708 | ENSBTAP00000012938 | EBNA1 binding protein 2. | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.996 |
EBNA1BP2 | MAK16 | ENSBTAP00000028708 | ENSBTAP00000044825 | EBNA1 binding protein 2. | Protein MAK16 homolog. | 0.993 |
EBNA1BP2 | MRTO4 | ENSBTAP00000028708 | ENSBTAP00000015861 | EBNA1 binding protein 2. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.996 |
EBNA1BP2 | NIFK | ENSBTAP00000028708 | ENSBTAP00000031516 | EBNA1 binding protein 2. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.997 |
EBNA1BP2 | NIP7 | ENSBTAP00000028708 | ENSBTAP00000002182 | EBNA1 binding protein 2. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. | 0.979 |
EBNA1BP2 | NOC2L | ENSBTAP00000028708 | ENSBTAP00000021980 | EBNA1 binding protein 2. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.997 |
EBNA1BP2 | PES1 | ENSBTAP00000028708 | ENSBTAP00000010163 | EBNA1 binding protein 2. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.998 |
EBNA1BP2 | RSL1D1 | ENSBTAP00000028708 | ENSBTAP00000019422 | EBNA1 binding protein 2. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage; Belongs to the universal ribosomal protein uL1 family. Highly divergent. | 0.994 |
EBNA1BP2 | WDR12 | ENSBTAP00000028708 | ENSBTAP00000020499 | EBNA1 binding protein 2. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.993 |
EBNA1BP2 | WDR74 | ENSBTAP00000028708 | ENSBTAP00000012489 | EBNA1 binding protein 2. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL. | 0.990 |