STRINGSTRING
PCDH18 PCDH18 FAM222A FAM222A C4H7orf57 C4H7orf57 RACGAP1 RACGAP1 NAP1L4 NAP1L4 TM4SF1 TM4SF1 PPP1R32 PPP1R32 LPAR1 LPAR1 PIP5K1B PIP5K1B EPHA7 EPHA7 TGFBR2 TGFBR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDH18Protocadherin-18; Potential calcium-dependent cell-adhesion protein. (1134 aa)    
Predicted Functional Partners:
FAM222A
Uncharacterized protein.
      
 0.570
C4H7orf57
Uncharacterized protein C7orf57 homolog.
   
 
 0.517
RACGAP1
Rac GTPase activating protein 1.
   
 
 0.510
NAP1L4
Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly.
   
  
 0.504
TM4SF1
Transmembrane 4 L six family member 1.
      
 0.490
PPP1R32
Protein phosphatase 1 regulatory subunit 32.
      
 0.481
LPAR1
Lysophosphatidic acid receptor 1; Receptor for lysophosphatidic acid (LPA). Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels. Signaling triggers an increase of cytoplasmic Ca(2+) levels. Activates RALA; this leads to the activation of phospholipase C [...]
      
 0.461
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
    
 
 0.457
EPHA7
EPH receptor A7.
   
 
 0.453
TGFBR2
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 
 0.453
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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