STRINGSTRING
PRPH PRPH NEFH NEFH NEFM NEFM NEFL NEFL PRSS33 PRSS33 H3C1 H3C1 ZNF385B ZNF385B H3C2 H3C2 PARP8 PARP8 PARP6 PARP6 PDE6G PDE6G
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
PRPHPeripherin; Class-III neuronal intermediate filament protein. (469 aa)    
Predicted Functional Partners:
NEFH
Neurofilament heavy; Belongs to the intermediate filament family.
    
0.909
NEFM
Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
    
0.906
NEFL
Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
    
 
0.903
PRSS33
Serine protease 33; Belongs to the peptidase S1 family.
      
 0.661
H3C1
Histone cluster 1, H3i.
      
 0.621
ZNF385B
Zinc finger protein 385B.
      
 0.569
H3C2
Histone cluster 1, H3g.
      
 0.550
PARP8
Poly [ADP-ribose] polymerase.
      
 0.436
PARP6
Poly [ADP-ribose] polymerase.
      
 0.436
PDE6G
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones.
      
 0.434
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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