node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCAS2 | BUD31 | ENSBTAP00000022204 | ENSBTAP00000061709 | Breast carcinoma amplified sequence 2. | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | 0.947 |
BCAS2 | CDC40 | ENSBTAP00000022204 | ENSBTAP00000059117 | Breast carcinoma amplified sequence 2. | Cell division cycle 40. | 0.984 |
BCAS2 | CDC5L | ENSBTAP00000022204 | ENSBTAP00000026654 | Breast carcinoma amplified sequence 2. | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | 0.999 |
BCAS2 | CRNKL1 | ENSBTAP00000022204 | ENSBTAP00000011148 | Breast carcinoma amplified sequence 2. | Crooked neck pre-mRNA splicing factor 1. | 0.950 |
BCAS2 | CTNNBL1 | ENSBTAP00000022204 | ENSBTAP00000010077 | Breast carcinoma amplified sequence 2. | Beta-catenin-like protein 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR) (By similarity). | 0.955 |
BCAS2 | EFTUD2 | ENSBTAP00000022204 | ENSBTAP00000068978 | Breast carcinoma amplified sequence 2. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | 0.977 |
BCAS2 | PLRG1 | ENSBTAP00000022204 | ENSBTAP00000029840 | Breast carcinoma amplified sequence 2. | Pleiotropic regulator 1; Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. | 0.999 |
BCAS2 | PRPF19 | ENSBTAP00000022204 | ENSBTAP00000019100 | Breast carcinoma amplified sequence 2. | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 comp [...] | 0.998 |
BCAS2 | SNW1 | ENSBTAP00000022204 | ENSBTAP00000010697 | Breast carcinoma amplified sequence 2. | SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, [...] | 0.968 |
BCAS2 | XAB2 | ENSBTAP00000022204 | ENSBTAP00000015097 | Breast carcinoma amplified sequence 2. | XPA binding protein 2. | 0.984 |
BUD31 | BCAS2 | ENSBTAP00000061709 | ENSBTAP00000022204 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Breast carcinoma amplified sequence 2. | 0.947 |
BUD31 | CDC40 | ENSBTAP00000061709 | ENSBTAP00000059117 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Cell division cycle 40. | 0.983 |
BUD31 | CDC5L | ENSBTAP00000061709 | ENSBTAP00000026654 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | 0.993 |
BUD31 | CRNKL1 | ENSBTAP00000061709 | ENSBTAP00000011148 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Crooked neck pre-mRNA splicing factor 1. | 0.996 |
BUD31 | CTNNBL1 | ENSBTAP00000061709 | ENSBTAP00000010077 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Beta-catenin-like protein 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR) (By similarity). | 0.873 |
BUD31 | EFTUD2 | ENSBTAP00000061709 | ENSBTAP00000068978 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | 0.988 |
BUD31 | PLRG1 | ENSBTAP00000061709 | ENSBTAP00000029840 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pleiotropic regulator 1; Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. | 0.985 |
BUD31 | PRPF19 | ENSBTAP00000061709 | ENSBTAP00000019100 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 comp [...] | 0.991 |
BUD31 | SNW1 | ENSBTAP00000061709 | ENSBTAP00000010697 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, [...] | 0.996 |
BUD31 | XAB2 | ENSBTAP00000061709 | ENSBTAP00000015097 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | XPA binding protein 2. | 0.996 |