STRINGSTRING
MOSPD3 MOSPD3 ZSWIM4 ZSWIM4 MOSPD2 MOSPD2 TBC1D22A TBC1D22A TNK2 TNK2 STARD3NL STARD3NL ENSBTAP00000071915 ENSBTAP00000071915 UBR2 UBR2 PCDH1 PCDH1 ZFYVE27 ZFYVE27 AUTS2 AUTS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOSPD3Motile sperm domain-containing protein 3. (236 aa)    
Predicted Functional Partners:
ZSWIM4
Zinc finger SWIM-type containing 4.
      
 0.721
MOSPD2
Uncharacterized protein.
    
 
 0.673
TBC1D22A
TBC1 domain family member 22A.
      
 0.663
TNK2
Activated CDC42 kinase 1; Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting [...]
      
 0.586
STARD3NL
STARD3 N-terminal like.
    
 
 0.569
ENSBTAP00000071915
MENTAL domain-containing protein.
    
 
 0.569
UBR2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.552
PCDH1
Protocadherin 1.
      
 0.501
ZFYVE27
Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. Acts as an adapter protein that facilitates the interaction of KIF5A with VAPA, VAPB, [...]
    
 
 0.490
AUTS2
Activator of transcription and developmental regulator AUTS2.
      
 0.483
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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