STRINGSTRING
ZAR1L ZAR1L KPNA7 KPNA7 BTG4 BTG4 WEE2 WEE2 DND1 DND1 RASL11A RASL11A RNF34 RNF34 GDF9 GDF9 RFC3 RFC3 CALM2 CALM2 CNBP CNBP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZAR1LZAR1-like protein. (344 aa)    
Predicted Functional Partners:
KPNA7
Importin subunit alpha-8; Functions in nuclear protein import.
   
  
 0.654
BTG4
BTG anti-proliferation factor 4.
   
  
 0.612
WEE2
Wee1-like protein kinase.
   
  
 0.608
DND1
DND microRNA-mediated repression inhibitor 1.
   
  
 0.588
RASL11A
RAS like family 11 member A.
      
 0.568
RNF34
E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...]
      
 0.520
GDF9
Growth/differentiation factor 9; Required for ovarian folliculogenesis.
   
  
 0.440
RFC3
Replication factor C subunit 3; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
      
 0.435
CALM2
Uncharacterized protein; Belongs to the calmodulin family.
      
 0.429
CNBP
Cellular nucleic acid-binding protein; Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression (By similarity).
      
 0.407
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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