STRINGSTRING
ITPK1 ITPK1 MINPP1 MINPP1 IPPK IPPK IPMK IPMK INPP5J INPP5J ITPKA ITPKA INPP1 INPP1 INPP5K INPP5K ITPKC ITPKC ITPKB ITPKB INPP5A INPP5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ITPK1Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconver [...] (420 aa)    
Predicted Functional Partners:
MINPP1
Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family.
     
 0.975
IPPK
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.975
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.974
INPP5J
Inositol polyphosphate-5-phosphatase J.
     
 0.940
ITPKA
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.934
INPP1
Inositol polyphosphate 1-phosphatase; Belongs to the inositol monophosphatase superfamily.
     
 0.930
INPP5K
Inositol polyphosphate-5-phosphatase K.
     
  0.911
ITPKC
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.908
ITPKB
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.908
INPP5A
Inositol polyphosphate-5-phosphatase A.
     
 0.904
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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