node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AURKAIP1 | ERAL1 | ENSBTAP00000061171 | ENSBTAP00000020770 | Aurora kinase A interacting protein 1. | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | 0.923 |
AURKAIP1 | METTL17 | ENSBTAP00000061171 | ENSBTAP00000008681 | Aurora kinase A interacting protein 1. | Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family. | 0.554 |
AURKAIP1 | MTERF3 | ENSBTAP00000061171 | ENSBTAP00000001994 | Aurora kinase A interacting protein 1. | Mitochondrial transcription termination factor 3. | 0.405 |
AURKAIP1 | RBFA | ENSBTAP00000061171 | ENSBTAP00000047450 | Aurora kinase A interacting protein 1. | Ribosome binding factor A. | 0.634 |
AURKAIP1 | TFB1M | ENSBTAP00000061171 | ENSBTAP00000042644 | Aurora kinase A interacting protein 1. | Mitochondrial dimethyladenosine transferase 1; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily. | 0.887 |
BYSL | IMP4 | ENSBTAP00000013326 | ENSBTAP00000004184 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. | U3 small nucleolar ribonucleoprotein protein IMP4; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (By similarity). | 0.995 |
BYSL | POLRMT | ENSBTAP00000013326 | ENSBTAP00000020034 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | 0.451 |
BYSL | PWP2 | ENSBTAP00000013326 | ENSBTAP00000072174 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. | WD_REPEATS_REGION domain-containing protein. | 0.997 |
BYSL | TFB1M | ENSBTAP00000013326 | ENSBTAP00000042644 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. | Mitochondrial dimethyladenosine transferase 1; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily. | 0.889 |
ERAL1 | AURKAIP1 | ENSBTAP00000020770 | ENSBTAP00000061171 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | Aurora kinase A interacting protein 1. | 0.923 |
ERAL1 | METTL17 | ENSBTAP00000020770 | ENSBTAP00000008681 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family. | 0.773 |
ERAL1 | MTERF3 | ENSBTAP00000020770 | ENSBTAP00000001994 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | Mitochondrial transcription termination factor 3. | 0.788 |
ERAL1 | POLRMT | ENSBTAP00000020770 | ENSBTAP00000020034 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | 0.594 |
ERAL1 | RBFA | ENSBTAP00000020770 | ENSBTAP00000047450 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | Ribosome binding factor A. | 0.767 |
ERAL1 | TFAM | ENSBTAP00000020770 | ENSBTAP00000052192 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | Transcription factor A, mitochondrial; Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymeras [...] | 0.502 |
ERAL1 | TFB1M | ENSBTAP00000020770 | ENSBTAP00000042644 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | Mitochondrial dimethyladenosine transferase 1; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily. | 0.929 |
IMP4 | BYSL | ENSBTAP00000004184 | ENSBTAP00000013326 | U3 small nucleolar ribonucleoprotein protein IMP4; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (By similarity). | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. | 0.995 |
IMP4 | PWP2 | ENSBTAP00000004184 | ENSBTAP00000072174 | U3 small nucleolar ribonucleoprotein protein IMP4; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (By similarity). | WD_REPEATS_REGION domain-containing protein. | 0.996 |
IMP4 | TFB1M | ENSBTAP00000004184 | ENSBTAP00000042644 | U3 small nucleolar ribonucleoprotein protein IMP4; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (By similarity). | Mitochondrial dimethyladenosine transferase 1; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily. | 0.826 |
METTL17 | AURKAIP1 | ENSBTAP00000008681 | ENSBTAP00000061171 | Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family. | Aurora kinase A interacting protein 1. | 0.554 |