node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHRNA1 | CHRNA4 | ENSBTAP00000024298 | ENSBTAP00000022855 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Cholinergic receptor nicotinic alpha 4 subunit. | 0.782 |
CHRNA1 | CHRND | ENSBTAP00000024298 | ENSBTAP00000015135 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.815 |
CHRNA1 | CHRNG | ENSBTAP00000024298 | ENSBTAP00000048242 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Acetylcholine receptor subunit gamma; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.722 |
CHRNA1 | DOK7 | ENSBTAP00000024298 | ENSBTAP00000063739 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Docking protein 7. | 0.731 |
CHRNA1 | MUSK | ENSBTAP00000024298 | ENSBTAP00000003558 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Muscle associated receptor tyrosine kinase. | 0.707 |
CHRNA1 | MYOG | ENSBTAP00000024298 | ENSBTAP00000007923 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] | 0.748 |
CHRNA1 | RAPSN | ENSBTAP00000024298 | ENSBTAP00000028986 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Receptor associated protein of the synapse. | 0.783 |
CHRNA1 | SLURP1 | ENSBTAP00000024298 | ENSBTAP00000045831 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Secreted LY6/PLAUR domain containing 1. | 0.900 |
CHRNA1 | SYT15 | ENSBTAP00000024298 | ENSBTAP00000024426 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Uncharacterized protein. | 0.417 |
CHRNA4 | CHRNA1 | ENSBTAP00000022855 | ENSBTAP00000024298 | Cholinergic receptor nicotinic alpha 4 subunit. | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.782 |
CHRNA4 | CHRND | ENSBTAP00000022855 | ENSBTAP00000015135 | Cholinergic receptor nicotinic alpha 4 subunit. | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.671 |
CHRNA4 | CHRNG | ENSBTAP00000022855 | ENSBTAP00000048242 | Cholinergic receptor nicotinic alpha 4 subunit. | Acetylcholine receptor subunit gamma; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.680 |
CHRNA4 | SLURP1 | ENSBTAP00000022855 | ENSBTAP00000045831 | Cholinergic receptor nicotinic alpha 4 subunit. | Secreted LY6/PLAUR domain containing 1. | 0.901 |
CHRND | CHRNA1 | ENSBTAP00000015135 | ENSBTAP00000024298 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.815 |
CHRND | CHRNA4 | ENSBTAP00000015135 | ENSBTAP00000022855 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Cholinergic receptor nicotinic alpha 4 subunit. | 0.671 |
CHRND | CHRNG | ENSBTAP00000015135 | ENSBTAP00000048242 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Acetylcholine receptor subunit gamma; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.653 |
CHRND | DOK7 | ENSBTAP00000015135 | ENSBTAP00000063739 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Docking protein 7. | 0.776 |
CHRND | MUSK | ENSBTAP00000015135 | ENSBTAP00000003558 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Muscle associated receptor tyrosine kinase. | 0.798 |
CHRND | MYOG | ENSBTAP00000015135 | ENSBTAP00000007923 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] | 0.587 |
CHRND | RAPSN | ENSBTAP00000015135 | ENSBTAP00000028986 | Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Receptor associated protein of the synapse. | 0.860 |