node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DLL1 | HES5 | ENSBTAP00000067364 | ENSBTAP00000003221 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Hes family bHLH transcription factor 5. | 0.780 |
DLL1 | HES7 | ENSBTAP00000067364 | ENSBTAP00000016506 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Hes family bHLH transcription factor 7. | 0.444 |
DLL1 | LFNG | ENSBTAP00000067364 | ENSBTAP00000052963 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | 0.723 |
DLL1 | MESP2 | ENSBTAP00000067364 | ENSBTAP00000038578 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Mesoderm posterior bHLH transcription factor 2. | 0.533 |
DLL1 | NOTCH2 | ENSBTAP00000067364 | ENSBTAP00000073810 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Notch receptor 2. | 0.972 |
DLL1 | POFUT1 | ENSBTAP00000067364 | ENSBTAP00000074128 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Protein O-fucosyltransferase 1a. | 0.660 |
DLL1 | TBX6 | ENSBTAP00000067364 | ENSBTAP00000011919 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). | 0.540 |
DLL3 | DLL4 | ENSBTAP00000013852 | ENSBTAP00000013680 | Delta like canonical Notch ligand 3. | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.924 |
DLL3 | HES5 | ENSBTAP00000013852 | ENSBTAP00000003221 | Delta like canonical Notch ligand 3. | Hes family bHLH transcription factor 5. | 0.683 |
DLL3 | HES7 | ENSBTAP00000013852 | ENSBTAP00000016506 | Delta like canonical Notch ligand 3. | Hes family bHLH transcription factor 7. | 0.408 |
DLL3 | LFNG | ENSBTAP00000013852 | ENSBTAP00000052963 | Delta like canonical Notch ligand 3. | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | 0.659 |
DLL3 | MESP2 | ENSBTAP00000013852 | ENSBTAP00000038578 | Delta like canonical Notch ligand 3. | Mesoderm posterior bHLH transcription factor 2. | 0.527 |
DLL3 | NOTCH2 | ENSBTAP00000013852 | ENSBTAP00000073810 | Delta like canonical Notch ligand 3. | Notch receptor 2. | 0.996 |
DLL3 | TBX6 | ENSBTAP00000013852 | ENSBTAP00000011919 | Delta like canonical Notch ligand 3. | T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). | 0.425 |
DLL4 | DLL3 | ENSBTAP00000013680 | ENSBTAP00000013852 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Delta like canonical Notch ligand 3. | 0.924 |
DLL4 | HES5 | ENSBTAP00000013680 | ENSBTAP00000003221 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Hes family bHLH transcription factor 5. | 0.676 |
DLL4 | LFNG | ENSBTAP00000013680 | ENSBTAP00000052963 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | 0.705 |
DLL4 | NOTCH2 | ENSBTAP00000013680 | ENSBTAP00000073810 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Notch receptor 2. | 0.998 |
DLL4 | POFUT1 | ENSBTAP00000013680 | ENSBTAP00000074128 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Protein O-fucosyltransferase 1a. | 0.534 |
HES5 | DLL1 | ENSBTAP00000003221 | ENSBTAP00000067364 | Hes family bHLH transcription factor 5. | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.780 |