HIVEP1 protein (Homo sapiens) - STRING network view

STRING 9.05

HIVEP1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1; This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequ [...] (2718 aa)
		(Homo sapiens)
Predicted Functional Partners:
	BTRC	beta-transducin repeat containing; Substrate recognition component of a SCF (SKP1-CUL1-F- box p [...] (605 aa)	•	•	0.906
	FBXW11	F-box and WD repeat domain containing 11; Substrate recognition component of a SCF (SKP1-CUL1-F [...] (542 aa)	•	•	0.888
	CLIC4	chloride intracellular channel 4; Can insert into membranes and form poorly selective ion chann [...] (253 aa)		•	0.623
	SOX10	SRY (sex determining region Y)-box 10; Transcription factor that seems to function synergistica [...] (466 aa)	•		0.583
	IRF5	interferon regulatory factor 5 (514 aa)	•		0.569

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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