STRING 9.05 
  ATG4B protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ATG4B
ATG4 autophagy related 4 homolog B (S. cerevisiae); Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes (393 aa)
(Homo sapiens)
Predicted Functional Partners:
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta; Probably involved in formation of autophag [...] (125 aa)
      0.997
ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae); GABARAPL1 (GABARAPL2 or GABARAP or MAP1LC3)-m [...] (314 aa)
      0.892
GABARAPL2
GABA(A) receptor-associated protein-like 2; Involved in intra-Golgi traffic. Modulates intra-Go [...] (117 aa)
      0.881
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma; Probably involved in formation of autopha [...] (147 aa)
      0.866
GABARAP
GABA(A) receptor-associated protein; May play a role in intracellular transport of GABA(A) rece [...] (117 aa)
      0.836
GABARAPL1
GABA(A) receptors associated protein like 3 (pseudogene); Increases cell-surface expression of [...] (117 aa)
      0.816
ATG10
ATG10 autophagy related 10 homolog (S. cerevisiae); Plays a role in autophagy (By similarity). [...] (220 aa)
      0.798
STK3
Serine/threonine-protein kinase 3 (EC 2.7.11.1)(STE20-like kinase MST2)(MST-2)(Mammalian STE20- [...] (491 aa)
       0.768
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha; Probably involved in formation of autopha [...] (125 aa)
      0.755
ATG12
ATG12 autophagy related 12 homolog (S. cerevisiae); Required for autophagy (187 aa)
      0.751
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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