STRINGSTRING
LOC100356307 LOC100356307 PRDX6 PRDX6 EPHX1 EPHX1 ENSOCUP00000031113 ENSOCUP00000031113 CYP1A1 CYP1A1 GSS GSS CYP1B1 CYP1B1 CYP1A2 CYP1A2 GSR GSR CYP2A10 CYP2A10 ALDH3B1 ALDH3B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LOC100356307Glutathione S-transferase. (218 aa)    
Predicted Functional Partners:
PRDX6
Thioredoxin domain-containing protein.
   
 0.959
EPHX1
Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family.
   
 
 0.943
ENSOCUP00000031113
GST C-terminal domain-containing protein.
   
 0.929
CYP1A1
Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]
   
 
 0.926
GSS
Glutathione synthetase.
   
 0.920
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 
 0.917
CYP1A2
Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...]
   
 
 0.915
GSR
Glutathione-disulfide reductase.
   
 
 0.911
CYP2A10
Cytochrome P450 2A10; Catalyzes the oxygenation of a variety of substrates, including ethanol and procarcinogens such as N-nitrosodiethylamine and phenacetin. Exhibits a high coumarin 7-hydroxylase activity. Converts also testosterone to androstenedione.
   
 
 0.905
ALDH3B1
Aldedh domain-containing protein.
   
 0.904
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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