rtcA protein (Methanosaeta thermophila PT) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	rtcA	Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (337 aa)
		(Methanosaeta thermophila PT)
Predicted Functional Partners:
	rpoL	DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription [...] (91 aa)	•		0.869
	Mthe_1374	protein of unknown function UPF0027 (473 aa)	•	•	0.856
	Mthe_0005	RNA binding S1 domain protein (185 aa)	•		0.831
	Mthe_0006	methyltransferase small (209 aa)	•		0.821
	Mthe_1315	PHP C-terminal domain protein (588 aa)	•		0.752
	Mthe_0364	Ribose-5-phosphate isomerase (206 aa)		•	0.731
	Mthe_0002	Putative uncharacterized protein (202 aa)	•		0.713
	Mthe_0282	putative RNA methylase, NOL1/NOP2/sun family (302 aa)	•		0.690
	Mthe_1588	Phosphodiesterase, MJ0936 family (176 aa)	•		0.675
	Mthe_1373	protein of unknown function DUF101 (141 aa)	•		0.661

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth