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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (575 aa)
(Aeromonas hydrophila)
Predicted Functional Partners:
nueB
Pseudaminic acid synthase, NeuB (348 aa)
     •  0.899
ribD
Riboflavin biosynthesis protein RibD (369 aa)
     •  0.899
ribE-3
Riboflavin synthase, alpha subunit (217 aa)
     •  0.899
ribE-2
6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (194 aa)
     •  0.899
thiL
Thiamine-monophosphate kinase (319 aa)
     •  0.899
AHA_2980
Fructokinase (318 aa)
     •  0.899
ribE-1
Riboflavin synthase, alpha subunit (205 aa)
     •  0.899
aceA
Isocitrate lyase (437 aa)
•  •  • 0.817
AHA_2118
Phosphatase YniC (219 aa)
•    •  0.808
AHA_3603
Phosphatase YbhA (273 aa)
     •  0.800
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth