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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) (347 aa)
(Aeromonas hydrophila)
Predicted Functional Partners:
AHA_1990
GMP synthase (Glutamine-hydrolyzing) (529 aa)
•  • •• 0.988
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotid [...] (418 aa)
•    •• 0.977
purH
Bifunctional purine biosynthesis protein purH (530 aa)
     •  0.965
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of A [...] (215 aa)
     •• 0.945
guaB
Inosine-5'-monophosphate dehydrogenase (487 aa)
  •• •••0.942
AHA_0041
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (284 aa)
     •• 0.938
AHA_2486
Inosine-guanosine kinase (434 aa)
     •• 0.926
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthi [...] (155 aa)
  •  •  0.910
hpt
Hypoxanthine phosphoribosyltransferase (176 aa)
     •• 0.903
AHA_3155
5'-nucleotidase/2',3'-cyclic phosphodiesterase (663 aa)
     •  0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth