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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Cd40lg
CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (CD154 antigen) [Contains- CD40 ligand, membrane form; CD40 ligand, soluble form]; Cytokine that binds to TNFRSF5. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching (By similarity) (260 aa)
(Rattus norvegicus)
Predicted Functional Partners:
Tnfrsf5
tumor necrosis factor receptor superfamily, member 5 (289 aa)
    ••• 0.992
Cd80
CD80 antigen (321 aa)
      • 0.877
Cd86
CD86 antigen (303 aa)
      • 0.850
Ctla4
cytotoxic T-lymphocyte-associated protein 4 (223 aa)
      • 0.849
Cd4
T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (W3/25 antigen); Ac [...] (457 aa)
      • 0.848
Cd28
T-cell-specific surface glycoprotein CD28 precursor; Possibly involved in T-cell activation (By [...] (218 aa)
      • 0.817
Il2
Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF); Produced by T-cells in response t [...] (155 aa)
      • 0.756
Il10
Interleukin-10 precursor (IL-10) (Cytokine synthesis inhibitory factor) (CSIF); Inhibits the sy [...] (178 aa)
      • 0.751
Il12b
interleukin 12b precursor (332 aa)
      • 0.725
Ifng
Interferon gamma precursor (IFN-gamma); Produced by lymphocytes activated by specific antigens [...] (156 aa)
      • 0.720
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth