version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (171 aa)
(Escherichia coli O1)
Predicted Functional Partners:
pfs
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage [...] (232 aa)
    0.999
metB
Cystathionine gamma-synthase, PLP-dependent (404 aa)
     0.958
metE
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase; Catalyzes the transfer [...] (753 aa)
     0.951
metC
cystathionine beta-lyase (421 aa)
      0.912
malY
Bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon (390 aa)
       0.899
ECED1_3270
Putative aminotransferase (391 aa)
       0.899
metH
Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent (1232 aa)
       0.899
trmA
tRNA (Uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 54 [...] (366 aa)
       0.675
cysK
Cysteine synthase A, O-acetylserine sulfhydrolase A subunit (323 aa)
      0.651
KatF
RNA polymerase, sigma S (Sigma 38) factor; Sigma factors are initiation factors that promote th [...] (342 aa)
       0.597
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth