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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity (By similarity) (284 aa)
(Mycobacterium bovis 1173P2)
Predicted Functional Partners:
hisE
putative phosphoribosyl-AMP pyrophosphatase HisE (93 aa)
• •  •• 0.998
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to [...] (438 aa)
• •• •• 0.997
hisC
putative histidinol-phosphate aminotransferase hisC1 (380 aa)
• ••  • 0.983
hisI
putative phosphoribosyl-AMP 1,6 cyclohydrolase hisI (115 aa)
• •• •• 0.983
hisB
putative imidazole glycerol-phosphate dehydratase hisB (210 aa)
• ••  • 0.982
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and [...] (206 aa)
• ••  • 0.971
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and [...] (267 aa)
• ••  • 0.969
hisA
putative phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA; Involved [...] (245 aa)
• ••  • 0.967
prs
putative ribose-phosphate pyrophosphokinase prsA (Phosphoribosyl pyrophosphate synthetase) (PRP [...] (326 aa)
     •  0.931
pat
Putative phenylalanine aminotransferase; May catalyze the transamination reaction in phenylalan [...] (353 aa)
•  •  • 0.811
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth