rtcA protein (Pyrobaculum islandicum) - STRING interaction network

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	rtcA	Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (348 aa)
		(Pyrobaculum islandicum)
Predicted Functional Partners:
	Pisl_1219	protein of unknown function UPF0027 (484 aa)	•	•			•	0.882
	Pisl_1200	Ribose-5-phosphate isomerase (223 aa)			•		•	0.727
	Pisl_0763	Phosphodiesterase, MJ0936 family (168 aa)	•					0.675
	Pisl_1685	protein of unknown function DUF101 (147 aa)	•					0.668
	Pisl_0754	Proteasome endopeptidase complex (203 aa)	•					0.664
	Pisl_0747	methyltransferase small (202 aa)	•					0.624
	flpA	Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Ut [...] (235 aa)			•	•	•	0.608
	Pisl_0380	Ribose-phosphate pyrophosphokinase (285 aa)	•					0.604
	alaS	Alanyl-tRNA synthetase (892 aa)	•					0.551
	Pisl_0918	ubiquitin-associated- domain-containing protein (129 aa)	•					0.536

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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