aceK protein (Acidovorax sp. JS42) - STRING interaction network

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (609 aa)
		(Acidovorax sp. JS42)
Predicted Functional Partners:
	Ajs_3776	Acetyl-CoA acetyltransferases (396 aa)	•				0.869
	Ajs_2401	Isocitrate lyase (443 aa)	•		•	•	0.812
	Ajs_3778	Carbonate dehydratase (220 aa)	•				0.731
	Ajs_2297	isocitrate dehydrogenase, NADP-dependent (419 aa)	•	•		•	0.711
	Ajs_0006	Putative uncharacterized protein (201 aa)		•			0.643
	Ajs_2300	Isocitrate dehydrogenase, NADP-dependent (744 aa)	•				0.628
	Ajs_3775	Short-chain dehydrogenase/reductase SDR (222 aa)	•				0.592
	Ajs_3779	acyl-CoA dehydrogenase domain protein (396 aa)	•				0.579
	Ajs_0169	ProQ activator of osmoprotectant transporter ProP (289 aa)		•			0.573
	Ajs_3215	Putative primosomal replication protein (96 aa)		•			0.492

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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