Axin2 protein (Mus musculus) - STRING interaction network

Axin2 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Axin2	axin2; Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity) (840 aa)
		(Mus musculus)
Predicted Functional Partners:
	Ctnnb1	catenin (cadherin associated protein), beta 1; Involved in the regulation of cell adhesion and [...] (781 aa)	•	•	•		0.993
	Gsk3b	glycogen synthase kinase 3 beta; Participates in the Wnt signaling pathway. Implicated in the h [...] (420 aa)	•	•	•		0.958
	Csnk1e	casein kinase 1, epsilon; Casein kinases are operationally defined by their preferential utiliz [...] (416 aa)		•	•		0.913
	Apc	adenomatosis polyposis coli; Tumor suppressor. Promotes rapid degradation of CTNNB1 and partici [...] (2842 aa)	•	•	•		0.904
	Apc2	adenomatosis polyposis coli 2; Promotes rapid degradation of CTNNB1 and may function as a tumor [...] (2274 aa)	•	•	•		0.900
	Hint1	histidine triad nucleotide binding protein 1; Hydrolyzes adenosine 5'-monophosphoramidate subst [...] (126 aa)			•		0.886
	Prkci	protein kinase C, iota; Calcium-independent, phospholipid-dependent, serine- and threonine-spec [...] (586 aa)			•		0.866
	Mapk8	mitogen activated protein kinase 8; Responds to activation by environmental stress and pro- inf [...] (427 aa)			•		0.856
	Dvl1	dishevelled, dsh homolog 1 (Drosophila); May play a role in the signal transduction pathway med [...] (695 aa)		•	•	•	0.855
	Men1	multiple endocrine neoplasia 1; May be involved in DNA repair. Component of MLL- containing com [...] (616 aa)			•		0.853

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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