Pak3 protein (Mus musculus) - STRING interaction network

Pak3 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	Pak3	p21 (CDKN1A)-activated kinase 3; Key regulator of synapse formation and plasticity in the hippocampus (559 aa)
		(Mus musculus)
Predicted Functional Partners:
	Arhgef7	Rho guanine nucleotide exchange factor (GEF7); Acts as a RAC1 guanine nucleotide exchange facto [...] (741 aa)		•	•	•		0.998
	Cdc42	cell division cycle 42 homolog (S. cerevisiae); Plasma membrane-associated small GTPase which c [...] (191 aa)		•	•	•		0.991
	Rac3	RAS-related C3 botulinum substrate 3; Plasma membrane-associated small GTPase which cycles betw [...] (192 aa)		•	•			0.971
	Arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; Acts as a RAC1 guanine nucleotide exchang [...] (770 aa)		•	•	•		0.949
	Nck1	non-catalytic region of tyrosine kinase adaptor protein 1 (377 aa)		•	•	•		0.935
	Lck	lymphocyte protein tyrosine kinase; Tyrosine kinase that plays an essential role for the select [...] (509 aa)			•	•	•	0.909
	Fyn	Fyn proto-oncogene; Implicated in the control of cell growth. Plays a role in the regulation of [...] (537 aa)			•	•	•	0.908
	Pak1	p21 (CDKN1A)-activated kinase 1; The activated kinase acts on a variety of targets. Likely to b [...] (544 aa)	•	•	•	•	•	0.906
	Pak2	p21 (CDKN1A)-activated kinase 2; The activated kinase acts on a variety of targets. Full length [...] (524 aa)	•	•	•	•	•	0.905
	Nck2	non-catalytic region of tyrosine kinase adaptor protein 2 (380 aa)		•	•			0.900

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth

Server load: low (34%)

Link to this page