rtcA protein (Pyrobaculum calidifontis) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	rtcA	Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (347 aa)
		(Pyrobaculum calidifontis)
Predicted Functional Partners:
	Pcal_0141	protein of unknown function UPF0027 (484 aa)	•	•			•	0.876
	Pcal_0662	Ribose-5-phosphate isomerase (222 aa)			•		•	0.711
	Pcal_0569	protein of unknown function DUF101 (147 aa)	•	•				0.701
	Pcal_1432	Phosphodiesterase, MJ0936 family (166 aa)	•					0.671
	Pcal_2008	Proteasome endopeptidase complex (203 aa)	•					0.661
	flpA	Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Ut [...] (234 aa)			•	•	•	0.651
	Pcal_0236	methyltransferase small (202 aa)	•					0.632
	Pcal_1127	Ribose-phosphate pyrophosphokinase (297 aa)	•					0.604
	alaS	Alanyl-tRNA synthetase (896 aa)	•					0.550
	Pcal_1994	ubiquitin-associated- domain-containing protein (122 aa)	•					0.535

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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