luxS protein (Actinobacillus pleuropneumoniae)

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	luxS	S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) (169 aa)
		(Actinobacillus pleuropneumoniae)
Predicted Functional Partners:
	mtnN	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage [...] (232 aa)	•	•	•	•	0.997
	metB	Cystathionine gamma-synthase (378 aa)	•		•	•	0.972
	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer o [...] (757 aa)	•		•	•	0.961
	APL_0701	O-acetylhomoserine (Thiol)-lyase (422 aa)	•		•	•	0.934
	metC	Cystathionine beta-lyase (396 aa)	•		•	•	0.922
	cysK	Cysteine synthase (316 aa)	•			•	0.803
	metK	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionin [...] (383 aa)	•			•	0.705
	APL_1217	Putative uncharacterized protein (888 aa)	•				0.684
	uvrB	UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of D [...] (673 aa)	•			•	0.642
	purT	Phosphoribosylglycinamide formyltransferase 2; Catalyzes two reactions- the first one is the pr [...] (393 aa)	•				0.634

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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