aceK protein (Burkholderia pseudomallei 668)

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (603 aa)
		(Burkholderia pseudomallei 668)
Predicted Functional Partners:
	wecB	UDP-N-acetylglucosamine 2-epimerase (404 aa)			•		0.899
	BPSS1125	Riboflavin biosynthesis protein RibD (401 aa)			•		0.899
	thiE	Thiamine-phosphate pyrophosphorylase (367 aa)			•		0.899
	thiL	Thiamine-monophosphate kinase (333 aa)			•		0.899
	BURPS668_3012	Riboflavin biosynthesis protein RibD (380 aa)			•		0.899
	cobT	Putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the [...] (352 aa)			•		0.899
	BPSL0826	Sorbitol dehydrogenase (258 aa)			•		0.899
	aceA	Isocitrate lyase (435 aa)	•	•		•	0.805
	BPSL2771	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family (183 aa)			•		0.800
	sixA	phosphohistidine phosphatase SixA (152 aa)			•		0.800

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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