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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Ext2
Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Protein sister of tout- velu); Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. Plays a central role in diffusion of morphogens hedgehog (hh), wingless (wg) and Decapentaplegic (dpp) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of Hh, Dpp and wg morphogens (717 aa)
(Drosophila melanogaster)
Predicted Functional Partners:
ttv
Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Protein tout-velu); Glycosyltransferase required for [...] (760 aa)
    • ••0.809
hh
Protein hedgehog precursor [Contains- Protein hedgehog N-product (Hh- Np) (N-Hh); Protein hedge [...] (471 aa)
      • 0.663
dpp
Protein decapentaplegic precursor (Protein DPP-C); Required during oogenesis for eggshell patte [...] (588 aa)
      • 0.519
dlp
dally-like CG32146-PB, isoform B (939 aa)
      • 0.510
NPF
neuropeptide F CG10342-PA; An integral part of the sensory system that mediates food signaling, [...] (102 aa)
      • 0.489
wg
Protein wingless precursor (Protein Wnt-1) (dWnt-1) (Protein int-1) (dInt-1); Binds as a ligand [...] (468 aa)
      • 0.460
dally
Division abnormally delayed protein precursor (Dally protein); Cell surface proteoglycan that b [...] (626 aa)
      • 0.455
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth