aceK protein (Enterobacter sp. 638) - STRING interaction network

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (573 aa)
		(Enterobacter sp. 638)
Predicted Functional Partners:
	Ent638_0219	Isocitrate lyase (434 aa)	•		•	•	0.890
	Ent638_0218	malate synthase A (533 aa)	•			•	0.819
	Ent638_1649	isocitrate dehydrogenase, NADP-dependent (416 aa)	•	•		•	0.710
	Ent638_0674	Carbonate dehydratase (220 aa)	•				0.587
	Ent638_2754	protein of unknown function DUF1228 (382 aa)		•			0.460
	Ent638_1742	Putative cytoplasmic protein (62 aa)		•			0.458
	proQ	ProP effector; Not exactly known; may be a structural element that influences the osmotic activ [...] (227 aa)		•			0.454
	Ent638_3849	GCN5-related N-acetyltransferase (162 aa)	•				0.452
	metA	Homoserine O-succinyltransferase (309 aa)	•			•	0.445
	queA	S-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moi [...] (356 aa)	•				0.402

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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