aceK protein (Pseudomonas mendocina) - STRING interaction network

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (572 aa)
		(Pseudomonas mendocina)
Predicted Functional Partners:
	Pmen_2396	isocitrate dehydrogenase, NADP-dependent (418 aa)	•	•	•	0.686
	Pmen_1791	protein of unknown function DUF6, transmembrane (296 aa)	•			0.592
	Pmen_2510	protein of unknown function UPF0153 (83 aa)		•		0.550
	Pmen_3120	Glucosylglycerol-phosphate synthase (752 aa)	•			0.435
	Pmen_2397	Isocitrate dehydrogenase, NADP-dependent (742 aa)	•			0.429
	queA	S-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moi [...] (347 aa)	•			0.400

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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