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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
rtcA
Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (334 aa)
(Metallosphaera sedula)
Predicted Functional Partners:
Msed_1752
protein of unknown function UPF0027 (460 aa)
•     • 0.853
Msed_0121
protein of unknown function DUF101 (135 aa)
•       0.675
Msed_0599
Putative uncharacterized protein (145 aa)
•       0.673
Msed_1723
Non-specific serine/threonine protein kinase (233 aa)
    • • 0.659
Msed_0007
putative RNA methylase, NOL1/NOP2/sun family (336 aa)
•       0.658
Msed_1790
Ribose-phosphate pyrophosphokinase (290 aa)
•       0.644
Msed_0739
Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein (164 aa)
•       0.642
Msed_1863
RNA binding S1 domain protein (191 aa)
•       0.625
Msed_0731
methyltransferase small (192 aa)
•       0.622
Msed_2287
Ribose-5-phosphate isomerase (227 aa)
   •  • 0.560
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth