KCNH2 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	KCNH2	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog); Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with [...] (1159 aa)
		(Homo sapiens)
Predicted Functional Partners:
	KCNE1	Potassium voltage-gated channel subfamily E member 1 (IKs producing slow voltage-gated potassiu [...] (129 aa)	•	•	•	0.999
	KCNE2	Potassium voltage-gated channel subfamily E member 2 (Minimum potassium ion channel-related pep [...] (123 aa)	•	•	•	0.998
	KCNQ1	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit [...] (676 aa)		•	•	0.996
	KCNA3	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit K [...] (575 aa)		•	•	0.985
	KCNA5	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit K [...] (613 aa)		•	•	0.982
	KCNQ3	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit [...] (872 aa)		•	•	0.982
	KCNA2	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit K [...] (499 aa)		•	•	0.982
	KCNQ2	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit [...] (880 aa)		•	•	0.981
	KCNA4	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit K [...] (545 aa)		•	•	0.981
	KCNA1	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit K [...] (495 aa)		•	•	0.980

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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