STRINGSTRING
LRCOL1 LRCOL1 C7orf31 C7orf31 FAM229B FAM229B NYAP1 NYAP1 FSCB FSCB CABS1 CABS1 LELP1 LELP1 SPATA24 SPATA24 EDDM3B EDDM3B TMEM114 TMEM114 IQCA1 IQCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LRCOL1Leucine-rich colipase-like protein 1; Leucine rich colipase like 1. (159 aa)    
Predicted Functional Partners:
C7orf31
Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.
      
 0.705
FAM229B
Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.
      
 0.702
NYAP1
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1; Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. Belongs to the NYAP family.
      
 0.664
FSCB
Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.
      
 0.594
CABS1
Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1.
      
 0.581
LELP1
Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family.
      
 0.581
SPATA24
Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).
      
 0.581
EDDM3B
Epididymal secretory protein E3-beta; Possible function in sperm maturation.
      
 0.567
TMEM114
Transmembrane protein 114.
      
 0.532
IQCA1
Dynein regulatory complex protein 11; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
      
 0.520
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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