lexA protein (Alkaliphilus metalliredigens) - STRING interaction network

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	lexA	LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) (206 aa)
		(Alkaliphilus metalliredigens)
Predicted Functional Partners:
	Amet_2658	Protein recA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the AT [...] (347 aa)	•	•	•	•	0.980
	Amet_4216	DNA-directed DNA polymerase (367 aa)	•			•	0.734
	Amet_4127	UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of D [...] (664 aa)	•			•	0.642
	Amet_0808	Putative metalloendopeptidase, glycoprotease family (359 aa)	•				0.635
	gltX	Glutamyl-tRNA synthetase (493 aa)	•				0.628
	Amet_0338	Sugar-phosphate isomerase, RpiB/LacA/LacB family (149 aa)	•				0.624
	Amet_0110	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also fo [...] (655 aa)	•				0.618
	Amet_2534	Phage integrase family protein (372 aa)	•				0.601
	Amet_2212	Anti-sigma factor antagonist (111 aa)	•				0.600
	Amet_0007	DNA gyrase, A subunit (830 aa)	•				0.586

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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