proS protein (Actinobacillus succinogenes) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	proS	Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (571 aa)
		(Actinobacillus succinogenes)
Predicted Functional Partners:
	Asuc_0657	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and [...] (395 aa)	•	0.799
	Asuc_1967	Undecaprenyl diphosphate synthase (239 aa)	•	0.798
	ispG	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclo [...] (371 aa)	•	0.796
	Asuc_1966	Phosphatidate cytidylyltransferase (288 aa)	•	0.796
	frr	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the t [...] (185 aa)	•	0.796
	pyrH	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) (237 aa)	•	0.795
	tsf	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to [...] (283 aa)	•	0.792
	rpsB	30S ribosomal protein S2 (241 aa)	•	0.787
	cysS	Cysteinyl-tRNA synthetase (459 aa)	•	0.763
	Asuc_1965	Putative membrane-associated zinc metalloprotease (442 aa)	•	0.761

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth