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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen III to yield coproporphyrinogen III (By similarity) (354 aa)
(Actinobacillus succinogenes)
Predicted Functional Partners:
Asuc_0382
Oxygen-independent coproporphyrinogen III oxidase (455 aa)
     0.996
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbil [...] (309 aa)
    0.987
Asuc_0667
Delta-aminolevulinic acid dehydratase (340 aa)
     0.979
Asuc_1871
Putative oxygen-independent coproporphyrinogen III oxidase (391 aa)
       0.966
Asuc_1562
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX (324 aa)
     0.958
hemL
Glutamate-1-semialdehyde 2,1-aminomutase (427 aa)
     0.942
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glut [...] (435 aa)
     0.907
ccmE
Cytochrome c-type biogenesis protein ccmE; Heme chaperone required for the biogenesis of c-type [...] (172 aa)
       0.842
Asuc_1983
protein of unknown function DUF416 (194 aa)
       0.835
Asuc_0845
Heme exporter protein CcmC (243 aa)
       0.827
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth