aceK protein (Anaeromyxobacter sp. Fw109-5) - STRING interaction network

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Your Input:
	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (575 aa)
		(Anaeromyxobacter sp. Fw109-5)
Predicted Functional Partners:
	Anae109_2963	Malate synthase A (1110 aa)	•		•	•	0.743
	Anae109_2186	isocitrate dehydrogenase, NADP-dependent (437 aa)	•	•		•	0.698
	Anae109_1774	Putative uncharacterized protein (370 aa)	•				0.650
	Anae109_1773	protein of unknown function DUF214 (841 aa)	•				0.650
	Anae109_1772	ABC transporter related (229 aa)	•				0.650
	Anae109_1771	PAS/PAC sensor hybrid histidine kinase (923 aa)	•				0.528
	Anae109_1770	Conserved hypothetical membrane protein (276 aa)	•				0.490
	Anae109_4132	Putative uncharacterized protein (280 aa)		•			0.464
	Anae109_2841	Carbonate dehydratase (196 aa)	•				0.453
	Anae109_1588	Isocitrate dehydrogenase, NADP-dependent (744 aa)	•				0.423

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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