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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (171 aa)
(Escherichia coli E24377A)
Predicted Functional Partners:
pfs
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage [...] (232 aa)
• •  •• 0.999
metB
O-succinylhomoserine (Thiol)-lyase (386 aa)
•    •• 0.958
metE
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase; Catalyzes the transfer [...] (753 aa)
•    •• 0.951
metC
cystathionine beta-lyase (395 aa)
•    •  0.913
metH
Methionine synthase (1227 aa)
     •  0.899
malY
MalY protein (390 aa)
     •  0.899
lsrR
DNA-binding transcriptional regulator; Regulates transcription of many different genes. In the [...] (317 aa)
      • 0.722
lsrK
Autoinducer 2 kinase lsrK; Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI- [...] (530 aa)
      • 0.710
metK
Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine from methioni [...] (384 aa)
•     • 0.687
trmA
tRNA (Uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 54 [...] (366 aa)
  •     0.666
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth