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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
rtcA
Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (338 aa)
(Escherichia coli E24377A)
Predicted Functional Partners:
rtcR
Sigma-54 dependent transcriptional regulator RtcR (532 aa)
     0.969
rtcB
RtcB protein (408 aa)
     0.952
EcE24377A_4570
Putative uncharacterized protein (254 aa)
      0.771
rpiA
Ribose-5-phosphate isomerase A (219 aa)
       0.710
EcE24377A_4569
SPFH domain/band 7 family protein (375 aa)
      0.699
prs
Ribose-phosphate pyrophosphokinase (315 aa)
       0.619
msm
Methylmalonyl-CoA mutase (714 aa)
       0.594
ECED1_0269
Putative uncharacterized protein (388 aa)
      0.477
ybiR
citrate transporter family protein (372 aa)
      0.466
norW
Nitric oxide reductase FlRd-NAD(+) reductase; One of at least two accessory proteins for anaero [...] (377 aa)
       0.456
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth