version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) (206 aa)
(Bacillus pumilus)
Predicted Functional Partners:
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the AT [...] (346 aa)
    0.981
gltX
Glutamyl-tRNA synthetase (483 aa)
       0.651
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of D [...] (661 aa)
      0.641
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dep [...] (288 aa)
       0.631
yneA
Cell division suppressor protein yneA; Inhibits cell division during the SOS response. Affects [...] (103 aa)
       0.628
gcp
O-sialoglycoprotein endopeptidase (342 aa)
       0.627
ywlF
Ribose-5-phosphate isomerase B (149 aa)
       0.626
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for [...] (666 aa)
       0.623
spoIIAA
stage II sporulation anti-anti-sigma factor (117 aa)
       0.607
BPUM_3065
MATE family multi antimicrobial extrusion protein (441 aa)
      0.594
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth