lexA protein (Salmonella enterica SPB7)

STRING 9.05

lexA protein (Salmonella enterica SPB7) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	lexA	LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) (202 aa)
		(Salmonella enterica SPB7)
Predicted Functional Partners:
	recA	recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the A [...] (353 aa)	•		•	•	•	0.991
	dinB	DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagen [...] (351 aa)	•				•	0.966
	uvrB	excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing o [...] (673 aa)	•				•	0.937
	umuC	DNA polymerase V subunit UmuC (422 aa)	•				•	0.892
	sulA	SOS cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Acc [...] (169 aa)	•	•	•		•	0.887
	recN	recombination and repair protein (553 aa)	•		•		•	0.879
	dnaN	DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible [...] (366 aa)	•	•			•	0.839
	rpsR	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the [...] (75 aa)	•				•	0.837
	dnaE	DNA polymerase III subunit alpha (1144 aa)	•				•	0.835
	dinF	DNA-damage-inducible SOS response protein (441 aa)	•				•	0.833

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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