mutM protein (Methylobacterium sp. 446)

STRING 9.05

mutM protein (Methylobacterium sp. 446) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	mutM	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) (297 aa)
		(Methylobacterium sp. 446)
Predicted Functional Partners:
	M446_1034	dephospho-CoA kinase (204 aa)	•	•	•	0.964
	M446_0678	DNA polymerase I (1016 aa)	•		•	0.948
	M446_6939	A/G-specific adenine glycosylase (405 aa)	•		•	0.903
	M446_5992	DNA polymerase III, alpha subunit (1168 aa)	•		•	0.846
	recA	recA protein; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the AT [...] (363 aa)	•		•	0.836
	M446_6614	ribonuclease III (244 aa)	•		•	0.823
	M446_2583	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of mis [...] (234 aa)	•		•	0.800
	M446_2100	pyridoxamine 5'-phosphate oxidase (210 aa)	•		•	0.798
	M446_2499	excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing [...] (970 aa)			•	0.798
	M446_4249	endonuclease III (249 aa)			•	0.796

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes

Server load: low (26%)

Permalink