mutM protein (Burkholderia cenocepacia J2315)

STRING 9.05

mutM protein (Burkholderia cenocepacia J2315) - STRING network view

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	mutM	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) (275 aa)
		(Burkholderia cenocepacia J2315)
Predicted Functional Partners:
	coaE	dephospho-CoA kinase (202 aa)	•	•		•	0.970
	resA	DNA polymerase I (917 aa)	•			•	0.950
	mutY	putative A/G-specific adenine glycosylase (368 aa)	•			•	0.948
	recA	recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the A [...] (347 aa)	•			•	0.838
	ruvB	Holliday junction DNA helicase RuvB; The ruvA-ruvB complex in the presence of ATP renatures cru [...] (356 aa)			•	•	0.826
	dnaE	DNA polymerase III subunit alpha (1177 aa)	•			•	0.815
	BCAL2214	DNA polymerase IV (391 aa)	•			•	0.814
	dnaB	replicative DNA helicase (460 aa)	•			•	0.802
	pdxH	pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'- phosphate ( [...] (214 aa)	•			•	0.801
	ung	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of mis [...] (286 aa)	•			•	0.799

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