STRINGSTRING
COG0187 COG0187 COG0188 COG0188 COG1372 COG1372 COG0592 COG0592 COG1396 COG1396 COG1195 COG1195 COG0593 COG0593 COG1196 COG1196 COG1132 COG1132 COG0443 COG0443 COG4974 COG4974
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
Score
COG0187DNA gyrase/topoisomerase IV, subunit B    
Predicted Functional Partners:
COG0188
DNA gyrase/topoisomerase IV, subunit A
  
0.978
COG1372
Intein/homing endonuclease
 
  
0.910
COG0592
DNA polymerase III sliding clamp (beta) subunit, PCNA homolog
  
 
0.909
COG1396
Transcriptional regulator, contains XRE-family HTH domain
 
  
0.899
COG1195
Recombinational DNA repair ATPase RecF
  
  
0.893
COG0593
Chromosomal replication initiation ATPase DnaA
  
  
0.864
COG1196
Chromosome segregation ATPase Smc
  
 
0.840
COG1132
ABC-type multidrug transport system, ATPase and permease component
  
0.820
COG0443
Molecular chaperone DnaK (HSP70)
  
0.810
COG4974
Site-specific recombinase XerD
  
  
0.795
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