STRINGSTRING
cpt2 cpt2 MPN_113 MPN_113 ptc1 ptc1 B01_orf274 B01_orf274 K04_orf389 K04_orf389 hprK hprK infC infC rpmI rpmI rpLT rpLT A05_orf475 A05_orf475
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpt2Acyltransferase; MPN114(new), 041(Himmelreich et al., 1996); Belongs to the carnitine/choline acetyltransferase family. (600 aa)    
Predicted Functional Partners:
MPN_113
G3P transporter-like protein; MPN113(new), 042(Himmelreich et al., 1996).
       0.779
ptc1
Protein phoshatase 2C-like protein; MPN247(new), 586(Himmelreich et al., 1996); similar to Swiss-Prot Accession Number P35182.
   
  
 0.658
B01_orf274
Hypothetical protein; MPN027(new), 127(Himmelreich et al., 1996).
   
  
 0.620
K04_orf389
Ser/Thr/Tyr protein kinase; MPN248(new), 585(Himmelreich et al., 1996); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
  
 0.616
hprK
HPr(Ser) kinase; Is a metabolite-sensitive enzyme that catalyzes the ATP-as well as probably the pyrophosphate-dependent phosphorylation of Ser-47 in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser- HPr). The regulatory role of HPrK/P in the physiology of M.pneumoniae is not known yet.
   
  
 0.611
infC
Translation initiation factor IF3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
       0.539
rpmI
Ribosomal protein L35; MPN116(new), 039(Himmelreich et al., 1996); Belongs to the bacterial ribosomal protein bL35 family.
       0.539
rpLT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
       0.529
A05_orf475
Permease; MPN421(new), 419(Himmelreich et al., 1996); To E.coli YihN.
  
    0.454
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.