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argI argI arcC arcC arcA-3 arcA-3 arcA-2 arcA-2 arcA arcA F10_orf565 F10_orf565 pmsR pmsR pheT pheT topA topA argS argS P65 P65
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
argIArgI; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (273 aa)    
Predicted Functional Partners:
arcC
Carbamate kinase; MPN307(new), 530(Himmelreich et al., 1996); Belongs to the carbamate kinase family.
  
 
 0.999
arcA-3
Arginine deiminase; MPN560(new), 282(Himmelreich et al., 1996); Belongs to the arginine deiminase family.
 
 
 0.990
arcA-2
(C-terminal, fragment); MPN305(new), 532(Himmelreich et al., 1996).
 
  
 0.978
arcA
(N-terminal, fragment); MPN304(new), 533(Himmelreich et al., 1996).
 
  
 0.941
F10_orf565
Amino acid permease; MPN308(new), 529(Himmelreich et al., 1996); see: MPN096.
  
  
 0.812
pmsR
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
 
   0.792
pheT
phenylalanyl-tRNA synthetase beta chain; MPN106(new), 049(Himmelreich et al., 1996); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.691
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.666
argS
arginyl-tRNA synthetase; MPN556(new), 286(Himmelreich et al., 1996).
  
  
 0.512
P65
Conserved hypothetical protein; MPN309(new), 528(Himmelreich et al., 1996).
       0.504
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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