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F10_orf357 F10_orf357 atpE atpE F10_orf218 F10_orf218 hmw2 hmw2 P65 P65 C09_orf910 C09_orf910 hmw3 hmw3 P200 P200 F11_orf358b F11_orf358b p30 p30 arcC arcC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
F10_orf357Conserved hypothetical protein; MPN311(new), 526(Himmelreich et al., 1996). (357 aa)    
Predicted Functional Partners:
atpE
ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.999
F10_orf218
Hypothetical protein; MPN312(new), 525(Himmelreich et al., 1996).
  
  
 0.937
hmw2
Cytadherence high molecular weight protein 2; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity).
  
  
 0.894
P65
Conserved hypothetical protein; MPN309(new), 528(Himmelreich et al., 1996).
     
 0.872
C09_orf910
Hypothetical protein; MPN119(new), 036(Himmelreich et al., 1996); contains j-domain of DnaJ and a domain common to cytadherence proteins.
    
 0.716
hmw3
Cytadherence accessory protein HMW3; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism.
   
  
 0.673
P200
Cyto adherence-like protein; Protein cytoskeleton-associated which plays a role in gliding motility and perhaps also in mucociliary clearance.
   
  
 0.642
F11_orf358b
Conserved hypothetical protein; MPN387(new), 451(Himmelreich et al., 1996).
   
  
 0.522
p30
30K adhesin-related protein; Adhesin necessary for successful cytadherence and virulence.
  
  
 0.474
arcC
Carbamate kinase; MPN307(new), 530(Himmelreich et al., 1996); Belongs to the carbamate kinase family.
  
    0.457
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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