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prfA prfA H91_orf453 H91_orf453 rplI rplI rpmF rpmF rplQ rplQ rpmA rpmA rpLT rpLT rpsL rpsL rplS rplS rplU rplU rplC rplC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (359 aa)    
Predicted Functional Partners:
H91_orf453
Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent).
  
 
 0.998
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
 
 0.994
rpmF
Ribosomal protein L32; MPN540(new), 302(Himmelreich et al., 1996); Belongs to the bacterial ribosomal protein bL32 family.
  
 
 0.993
rplQ
Ribosomal protein L17; MPN192(new), 640(Himmelreich et al., 1996).
  
 
 0.992
rpmA
Ribosomal protein L27; MPN327(new), 510(Himmelreich et al., 1996); Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.992
rpLT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
  
 
 0.991
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
  
 
 0.991
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 
 0.991
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.990
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.989
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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