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MPN_418 MPN_418 alaS alaS glpQ glpQ A05_orf475 A05_orf475 mnmA mnmA H91_orf453 H91_orf453 ftsY ftsY smc smc NadD NadD A05_orf129 A05_orf129 ylxM ylxM
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
MPN_418Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (140 aa)    
Predicted Functional Partners:
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.887
glpQ
Glycerophosphoryl diester phosphodiesterase; MPN420(new), 420(Himmelreich et al., 1996); To glycerophosphoryl diester phosphodiesterases (EC 3.1.4.46).
  
    0.635
A05_orf475
Permease; MPN421(new), 419(Himmelreich et al., 1996); To E.coli YihN.
  
    0.625
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.511
H91_orf453
Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent).
  
    0.472
ftsY
Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
  
    0.457
smc
SMC family, chromosome/DNA binding/protecting functions; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
    0.437
NadD
Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity.
     
 0.434
A05_orf129
Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996).
  
    0.421
ylxM
Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity).
  
    0.421
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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